Synthetic Cells–Self-Assembling Polymer Membranes and Bioadhesive Colloids

We summarize developments in the construction of synthetic cells made from polymers, with a particular focus on mimicking the structure and behavior of blood cells. Two basic themes emerge—the use of block copolymers to make polmer vesicles and the functionalization of colloidal or polymeric microspheres with cell-like adhesive properties. Both platforms provide a means for building the complex hierarchy that is characteristic of biological cells, while also incorporating novel and perhaps superior properties of material strength, specific targeting, and controlled release.