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Annual Review of Biomedical Engineering

Volume 1, 1999

Review Article

Imaging Transgenic Animals

T. F. Budinger, D. A. Benaron, and A. P. Koretsky
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Affiliations: ¹Department of Bioengineering and Center for Functional Imaging, Lawrence Berkeley National Laboratory, University of California, Berkeley, California 94720; email: [email protected] ²Hansen Experimental Physics Laboratory (HEPL), Department of Physics, Stanford University, Stanford, CA 94305; ³Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213
Vol. 1:611-648 (Volume publication date August 1999) https://doi.org/10.1146/annurev.bioeng.1.1.611
© Annual Reviews

Abstract

▪ Abstract

Transgenic and eugenic animals as small as 30 g can be studied noninvasively by radionuclides with resolutions of 1–2 mm, by MRI with resolution of 100 μm and by light fluorescence and bioluminescence with high sensitivities. The technologies of radionuclide emission, magnetic resonance imaging, magnetic resonance spectroscopy, optical tomography, optical fluorescence and optical bioluminescence are currently being applied to small-animal studies. These technologies and examples of their applications are reviewed in this chapter.

Keyword(s): emission imaging, gene expression, magnetic resonance imaging, magnetic resonance spectroscopy, optical imaging, positron emission tomography, single photon tomography, transgenic

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1999-08-01

2024-04-26

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Imaging Transgenic Animals

Annual Review of Biomedical Engineering 1, 611 (1999); https://doi.org/10.1146/annurev.bioeng.1.1.611

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