A PERSONAL SIXTY-YEAR TOUR OF GENETICS AND MEDICINE

Literature Cited

1. Baltimore D. 1970. RNA-dependent DNA polymerase in virions of RNA tumour viruses. Nature 226:1209–11 [Google Scholar]
2. Benedict WF, Murphree AL, Banerjee A, Spina CA, Sparkes MC. et al. 1983. Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene. Science 219:973–75 [Google Scholar]
3. Borsook H, Keighley GL. 1935. Continuing metabolism of nitrogen in animals. Proc. R. Soc. London 118:488–521 [Google Scholar]
4. Brenner S, Jacob F, Meselson M. 1961. An unstable intermediate carrying information from genes to ribosomes for protein synthesis. Nature 190:576–81 [Google Scholar]
5. Cavenee WK, Dryja TP, Phillips RA, Benedict WF, Godbout R. et al. 1983. Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 305:779–84 [Google Scholar]
6. Childs B. 1999. Genetic Medicine: A Logic of Disease Baltimore: Johns Hopkins Univ. Press316 pp.
7. Eker R, Mossige J. 1961. A dominant gene for renal adenomas in the rat. Nature 189:858–59 [Google Scholar]
8. Ellerman V, Bang O. 1908. Experimentelle Leukämie bei Hühnerm. Zentralbl. Bakteriol. Parasitenkd Orig. Abt. 1 46:595–609 [Google Scholar]
9. Francke U, Kung F. 1976. Sporadic bilateral retinoblastoma and 13q-chromoso-mal deletion. Med. Pediatr. Oncol. 2:379–85 [Google Scholar]
10. Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM. et al. 1986. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323:643–46 [Google Scholar]
11. Gaucher PC. 1882. De l'epithelioma primitif de la rate: hypertrophie idiopathique de la rate sans leucemie PhD thesis. Faculté de Médecine de Paris 31 pp.
12. Godbout R, Dryja TP, Squire J, Gallie BL, Phillips RA. 1983. Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma. Nature 304:451–53 [Google Scholar]
13. Gros F, Hiatt H, Gilbert W, Kurland CG, Risebrough RW. et al. 1961. Unstable ribonucleic acid revealed by pulse labelling of Escherichia coli. Nature 190:581–85 [Google Scholar]
14. Hallett WY, Knudson AG, Massey FJ. 1965. Absence of detrimental effect of the carrier state for the cystic fibrosis gene. Am. Rev. Respir. Dis. 92:714–24 [Google Scholar]
15. Hino O, Klein-Szanto AJ, Freed JJ, Testa JR, Brown DQ. et al. 1993. Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer. Proc. Natl. Acad. Sci. USA 90:327–31 [Google Scholar]
16. Hunt JA, Ingram VM. 1958. Allelomorphism and the chemical differences of the human haemoglobins A, S and C. Nature 181:1062–63 [Google Scholar]
17. Jacob F, Monod J. 1961. Genetic regulatory mechanisms in the synthesis of proteins. J. Mol. Biol. 3:318–56 [Google Scholar]
18. Kaback MM. 2001. Screening and prevention in Tay-Sachs disease: origins, update, and impact. Adv. Genet. 44:253–65 [Google Scholar]
19. Knudson AG. 1951. Mixed adrenal disease of infancy. J. Pediatr. 39:408–23 [Google Scholar]
20. Knudson AG. 1961. Inborn errors of sphingolipid metabolism. Am. J. Clin. Nutr. 9:55–62 [Google Scholar]
21. Knudson AG. 1965. Ethnic differences in childhood leukemia as revealed by a study of antecedent variables. Cancer 18:815–18 [Google Scholar]
22. Knudson AG. 1965. Genetics and Disease New York: McGraw Hill294 pp.
23. Knudson AG. 1966. Congenital viral infection and human disease. Am. Nat. 100:162–64 [Google Scholar]
24. Knudson AG. 1971. Mutation and cancer: statistical study of retinoblastoma. Proc. Natl. Acad. Sci. USA 68:820–23 [Google Scholar]
25. Knudson AG. 1973. Founder effect in Tay-Sachs disease. Am. J. Hum. Genet. 25:108 [Google Scholar]
26. Knudson AG. 1978. Retinoblastoma: a prototypic hereditary neoplasm. Semin. Oncol. 5:57–60 [Google Scholar]
27. Knudson AG. 1979. Presidential address. Our load of mutations and its burden of disease. Am. J. Hum. Genet. 31:401–13 [Google Scholar]
28. Knudson AG, Brodetsky AM, Baluda MA. 1967. Transient inhibition of avian myeloblastosis virus reproduction by amethopterin and fluorodeoxyuridine. J. Virol. 1:1150–57 [Google Scholar]
29. Knudson AG, Strong LC, Anderson DE. 1973. Heredity and cancer in man. Prog. Med. Genet. 9:113–58 [Google Scholar]
30. Knudson AG, Kaplan WD. 1962. Genetics of the sphingolipidoses. In Cerebral Sphingolipidoses ed. SM Aronson, BW Volk pp. 395–411 New York: Academic [Google Scholar]
31. Knudson AG, Meadows AT, Nichols WW, Hill R. 1976. Chromosomal deletion and retinoblastoma. N. Engl. J. Med. 295:1120–23 [Google Scholar]
32. Knudson AG, Owen RD. 1968. Molecular genetics and disease resistance. In Structural Chemistry and Molecular Biology ed. A Rich, N Davidson pp. 281–84 San Francisco: Freeman [Google Scholar]
33. Knudson AG, Rothman PE. 1953. Hypervitaminosis A. A review with a discussion of vitamin A. Am. J. Dis. Child 85:316–34 [Google Scholar]
34. Knudson AG, Strong LC. 1972. Mutation and cancer: a model for Wilms' tumor of the kidney. J. Natl. Cancer Inst. 48:313–24 [Google Scholar]
35. Knudson AG, Strong LC. 1972. Mutation and cancer: neuroblastoma and pheochromocytoma. Am. J. Hum. Genet. 24:514–32 [Google Scholar]
36. Knudson AG, Wayne L, Hallett WY. 1967. On the selective advantage of cystic fibrosis heterozygotes. Am. J. Hum. Genet. 19:388–92 [Google Scholar]
37. Kobayashi T, Hirayama Y, Kobayashi E, Kubo Y, Hino O. 1995. A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer. Nat. Genet. 9:70–74 [Google Scholar]
38. Kruh J, Borsook H. 1956. Hemoglobin synthesis in rabbit reticulocytes in vitro. J. Biol. Chem. 220:905–15 [Google Scholar]
39. Lejeune J, Gautier M, Turpin R. 1959. Etude des chromosomes somatiques de neuf enfants mongoliens. C. Rend. Acad. Sc. 248:1721–22 [Google Scholar]
40. Nowell P, Hungerford D. 1960. A minute chromosome in human chronic granulocytic leukemia. Science 132:1497 [Google Scholar]
41. Okada S, O'Brien JS. 1969. Tay-Sachs disease: generalized absence of a beta-D-N-acetylhexosaminidase component. Science 165:698–700 [Google Scholar]
42. Owen RD. 1945. Immunogenetic consequences of vascular anastomoses between bovine twins. Science 102:400–1 [Google Scholar]
43. Pauling L, Itano HA. 1949. Sickle cell anemia, a molecular disease. Science 110:543–48 [Google Scholar]
44. Rennebeck G, Kleymenova EV, Anderson R, Yeung RS, Artzt K. et al. 1998. Loss of function of the tuberous sclerosis 2 tumor suppressor gene results in embryonic lethality characterized by disrupted neuroepithelial growth and development. Proc. Natl. Acad. Sci. USA 95:15629–34 [Google Scholar]
45. Rous P. 1911. A sarcoma of the fowl transmissible by an agent separable from the tumor cells. J. Exp. Med. 13:397–411 [Google Scholar]
46. Schoenheimer R. 1942. The Dynamic State of Body Constituents Cambridge: Harvard Univ. Press78 pp.
47. Schweet R, Lamfrom H, Allen E. 1958. The synthesis of hemoglobin in a cell-free system. Proc. Natl. Acad. Sci. USA 44:1029–35 [Google Scholar]
48. Sparkes RS, Sparkes MC, Wilson MG, Towner JW, Benedict W. et al. 1980. Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14. Science 208:1042–44 [Google Scholar]
49. Stehelin D, Varmus HE, Bishop JM, Vogt PK. 1976. DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature 260:170–73 [Google Scholar]
50. Temin HM, Mizutani S. 1970. RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature 226:1211–13 [Google Scholar]
51. Tucker M, Goldstein A, Dean M, Knudson A. 2000. National Cancer Institute Workshop Report: the phakomatoses revisited. J. Natl. Cancer Inst. 92:530–33 [Google Scholar]
52. Vilenchik MM, Knudson AG. 2003. Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer. Proc. Natl. Acad. Sci. USA 100:12871–76 [Google Scholar]
53. Yeung RS, Xiao GH, Jin F, Lee WC, Testa JR. et al. 1994. Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene. Proc. Natl. Acad. Sci. USA 91:11413–16 [Google Scholar]