Spatiotemporal Basis of Innate and Adaptive Immunity in Secondary Lymphoid Tissue: Video 7

A video from the 2014 review by Hai Qi, Wolfgang Kastenmüller, and Ronald N. Germain, "Spatiotemporal Basis of Innate and Adaptive Immunity in Secondary Lymphoid Tissue," from the Annual Review of Cell and Developmental Biology.

Shown: Dynamic behavior of naïve CD4+ and CD8+ T cells in the lymph node

CD4⁺ T cells (red) and CD8⁺ T cells (green) in the inguinal LN (Mandl JN, Liou R, Klauschen F, Vrisekoop N, Monteiro JP, et al. 2012. Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4⁺ and CD8⁺ T cells. Proc. Natl. Acad. Sci. USA 109:18036–41).