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Flaviviridae Replication Organelles: Oh, What a Tangled Web We Weave: Video 1

Abstract

A video from the 2015 review by David Paul and Ralf Bartenschlager, "Flaviviridae Replication Organelles: Oh, What a Tangled Web We Weave," from the Annual Review of Virology

Shown: Morphology of dengue virus (DV) replication organelles. Electron tomography with 3D reconstruction reveals the continuity of endoplasmic reticulum membranes (yellow) and DV-induced vesicular invaginations. Budding of DV progeny virions (red) juxtaposed to vesicle openings is frequently observed. Golgi membranes are depicted in green. Adapted with permission from Welsch et al., Cell Host Microbe 5:365–75 (2009). 

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