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Flaviviridae Replication Organelles: Oh, What a Tangled Web We Weave: Video 2

Abstract

A video from the 2015 review by David Paul and Ralf Bartenschlager, "Flaviviridae Replication Organelles: Oh, What a Tangled Web We Weave," from the Annual Review of Virology

Shown: Morphology of hepatitis C virus (HCV) replication organelles consisting primarily of double-membrane vesicles (DMVs). Color-coded 3D surface model shows outer membranes of DMVs in light brown and inner membranes in orange. DMVs emerge as protrusions from the endoplasmic reticulum (dark brown) and are thus commonly found to be connected to this compartment. Small single-membrane vesicles are depicted in pink, intermediate filaments in dark blue, and Golgi membranes in green. Reproduced with permission from Romero-Brey et al., PLOS Pathog. 8:e1003056 (2012).

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